While it has long been assumed that the majority of the population achieves adequate levels of vitamin D through exposure to the sun, the biosynthesis of the nutrient is affected by time of day, seasons, location, smog/pollution, clothing and sunscreen. Vitamin D3 also produces a two- to three- fold greater storage of vitamin D than D2. According to recent research from human clinical trials, vitamin D3 is approximately 87% more potent in raising and maintaining serum 25(OH)D concentrations, than the vitamin D2 form. While vitamin D is available in both the D2 and D3 forms as supplements, studies have found vitamin D3 is the preferable form. D3 is then metabolized to calcitriol, a steroid hormone that helps regulate a variety of genes through the vitamin D receptor (VDR). When calcium and phosphorus levels dip in the body, parathyroid hormone (PTH) is released to increase vitamin D conversion to the active form. Vitamin D3 is also the form which the body derives from dietary cholesterol. Vitamin D3 is the bioidentical form of vitamin D synthesized in the skin following exposure to sunlight.

Our bodies make vitamin D by converting vitamin D2 (ergocaliferol) into D3 (cholecalciferol). Known as the sunshine vitamin, one of the key roles of vitamin D is maintaining serum calcium and phosphorous balance.

For those who require an immediate boost in their vitamin D status, the vitamin D3 50,000 IU formulation is a convenient, effective way to get the substantial support they need. This often includes elderly patients with low vitamin D levels, those with challenges in absorbing and maintaining vitamin D levels, and overweight patients with an elevated body mass index that impairs vitamin D circulation. Vitamin D3 50,000 IU is ideal for those who have difficulty achieving and maintaining peak vitamin D levels. At the same time, deficiency and insufficiency of this important nutrient has reached epidemic proportions around the world, making the achievement of optimal levels extremely important to overall health and wellbeing. A growing body of research highlights vitamin D’s important role in supporting other body systems, including cardiovascular and blood sugar balance, musculoskeletal strength, and neurological and immune function, enabled by vitamin D’s ability to target over 200 different genes throughout the body. Vitamin D is a steroid vitamin, a group of fat-soluble pro- hormones that are best known for the role they play in supporting bone health and aiding in the absorption of calcium and phosphate from the gastrointestinal tract.

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